Francesco Alessandri

Work Experience:
From 01/11/2009
Policlinico Umberto I, Viale del Policlinico 155, 00168 Rome
Intensivist doctor

Education and Training:
2006 to 2009 University of Rome Sapienza
Specialist in Anesthesiology and Critical care
70/70 cum laude
1999 to 2005 University of Rome Sapienza
Degree in Medicine
110/110 cum laude

Additional Information:
Partecipation to follow medical trials:
– Principal investigator INTEREST trial NCT
– Sub-investigator SUPERNOVA trial NCT02282657 interventional study
– Sub-investigator MSD-MK-7655A- FEDEX interventional study
– Sub-investigator APRICOT trial NCT01878760 observational study

Publications:
Goligher EC, Combes A, Brodie D, Ferguson ND, Pesenti AM, Ranieri VM, Slutsky AS; for the SUPERNOVA investigators (European Society of Intensive Care Medicine trials group) and for the International ECMO Network (ECMONet). Determinants of the effect of extracorporeal carbon dioxide removal in the SUPERNOVA trial: implications for trial design. Intensive Care Med. 2019 Aug 20.

Migliara G, Di Paolo C, Barbato D, Baccolini V, Salerno C, Nardi A, Alessandri F, Giordano A, Tufi D, Marinelli L, Cottarelli A, De Giusti M, Marzuillo C, De Vito C, Antonelli G, Venditti M, Tellan G, Ranieri MV, Villari P. Multimodal surveillance of healthcare associated infections in an intensive care unit of a large teaching hospital. Ann Ig. 2019 Sep-Oct;31(5):399-413.

Baccolini V, D’Egidio V, de Soccio P, Migliara G, Massimi A, Alessandri F, Tellan G, Marzuillo C, De Vito C, Ranieri MV, Villari P. Effectiveness over time of a multimodal intervention to improve compliance with standard hygiene precautions in an intensive care unit of a large teaching hospital. Antimicrob Resist Infect Control. 2019; 8:92.

Alessandri F, Antenucci G, Piervincenzi E, Buonopane C, Bellucci R, Andreoli C, Alunni Fegatelli D, Ranieri MV, Bilotta F. Ultrasound as a new tool in the assessment of airway difficulties. Eur J Anaesthesiol. 2019 Apr 3

Combes A, Fanelli V, Pham T, Ranieri VM; European Society of Intensive Care Medicine Trials Group and the “Strategy of Ultra-Protective lung ventilation with Extracorporeal CO2 Removal for New-Onset moderate to severe ARDS” (SUPERNOVA) investigators. Feasibility and safety of extracorporeal CO(2) removal to enhance protective ventilation in acute respiratory distress syndrome: the SUPERNOVA study. Intensive Care Med. 201; 45(5):592-600.

Ceccarelli G, Alessandri F, Sargentini V, D’Alessandro MD, Spaziante M, Bachetoni A, Morabito S, Venditti M. Impact of continuous renal replacement therapy (CRRT) and other extracorporeal support techniques on procalcitonin guided antibiotic therapy in critically ill patients with septic shock. Clin Chem Lab Med. 2018 Sep 11.

Spaziante M, Ceccarelli G, Al Moghazi S, Alessandri F, Venditti M. Specific dynamic of serum procalcitonin in critically ill patients affected by Gram-negative bacilli septic thrombophlebitis. Crit Care. 2018 Jul 23;22(1):178.

Pugliese F, Babetto C, Alessandri F, Ranieri VM. Prone Positioning for ARDS: still misunderstood and misused. J Thorac Dis. 2018 Jun;10(Suppl 17):S2079-S2082.

Extracorporeal CO2 Removal May Improve Renal Function of Patients with Acute Respiratory Distress Syndrome and Acute Kidney Injury: An Open-Label, Interventional Clinical Trial. Fanelli V, Cantaluppi V, Alessandri F, Costamagna A, Cappello P, Brazzi L, Pugliese F, Biancone L, Terragni P, Ranieri VM. Am J Respir Crit Care Med. 2018 Sep 1;198(5):687-690.

Russo A, Giuliano S, Ceccarelli G, Alessandri F, Giordano A, Brunetti G, Venditti M. Comparison of Septic Shock Due to Multidrug-Resistant Acinetobacter baumannii or Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae in Intensive Care Unit Patients. Antimicrob Agents Chemother. 2018 May 25;62(6).

Sargentini V, Collepardo D, D Alessandro M, Petralito G, Ceccarelli G, Alessandri F, Piciocchi A, Angeloni A, Venditti M, Bachetoni A. Role of biomarkers in adult sepsis and their application for a good laboratory practice: a pilot study. J Biol Regul Homeost Agents. 2017 Oct-Dec;31(4):1147-1154.

Molfino A, Alessandri F, Mosillo P, Dell’Utri D, Farcomeni A, Amabile MI, Laviano A. PTEN expression and its association with glucose control and calorie supplementation in critically ill patients. Clin Nutr. 2017 Nov 4. pii: S0261-5614(17)31394-8.

Alessandri F, Pugliese F, Mascia L, Ranieri MV. Intermittent extracorporeal CO2 removal in chronic obstructive pulmonary disease patients: a fiction or an option. Curr Opin Crit Care. 2018 Feb;24(1):29-34.

Alessandri F, Pugliese F, Ranieri VM. Mechanical ventilation: we have come a long way but still have a long road ahead. Lancet Respir Med. 2017 Dec;5(12):922-924.

Alessandri F, Pugliese F, Ranieri VM. The Role of Rescue Therapies in the Treatment of Severe ARDS. Respir Care. 2018 Jan;63(1):92-101.

Sanfilippo M, Alessandri F, Wefki Abdelgawwad Shousha AA, Sabba A, Cutolo A. Sugammadex and ideal body weight in bariatric surgery. Anesthesiol Res Pract. 2013;2013:389782.

Marandola M, Cilli T, Alessandri F, Tellan G, Caronna R, Chirletti P, Delogu G. Perioperative management in patients undergoing pancreatic surgery: the anesthesiologist’s point of view. Transplant Proc. 2008 May;40(4):1195-9.

Books Chapters:
1) Critical Care Update 2018 (ISCCM) ESCCM TODI S., ZIRPE K., KULKAREI A., METHA Y.
2) ECMO SPECIALIST TRAINING MANUAL 4TH EDITION ELSO
BROGAN T., ANNICH G, CORY ELLIS W., HANEY B., HEARD ML., LORUSSO R.
3) MANUALE DI ANESTESIA E TERAPIA INTENSIVA EDRA
RANIERI V.M., MASCIA L., TRITAPEPE L.

Comunications:
POINT OF CARE LUNG ULTRASOUND
26° Meeting ESCTAIC 22-24 09-2016 Timisoara, Romania

VENTILAZIONE MECCANICA NEL PAZIENTE CRITICO IN NEURORIANIMAZIONE
SIAARTI 2017 Rimini, Italia

MONITORING MECHANICAL VENTILATION
27° Meeting ESCTAIC 27-29 09-2018 Chisinau, Moldavia

ULTRASOUND FOR DETECTING DIFFICULT AIRWAY MANAGEMENT
27° Meeting ESCTAIC 27-29 09-2018 Chisinau, Moldavia

Teachings:
ANESTESIA CLINICA presso SCUOLA DI SPECIALIZZAZIONE FARMACOLOGIA CLINICA E TOSSICOLOGIA FROM 2010

SCUOLA DI SPECIALIZZAZIONE IN ANESTESIA, RIANIMAZIONE, MEDICINA
CRITICA E TERAPIA DEL DOLORE FROM 2018